Documenting Dupixent Eye Side Effects for a Potential Claim

Medically reviewed by licensed healthcare professionals · Legally reviewed by mass tort litigation specialists · Last updated: March 2026

Ocular (eye-related) side effects are consistently reported by Dupixent patients in clinical trials and post-market surveillance. If you've experienced eye issues while on Dupixent, proper documentation is the most important first step for both your medical care and any potential legal claim.

Commonly Reported Dupixent Eye Side Effects

The most frequently reported ocular adverse events in Dupixent clinical trials and patient reports include:

• Conjunctivitis: Inflammation of the conjunctiva (the clear tissue covering the white part of the eye), causing redness, itching, and discharge. Allergic conjunctivitis is particularly common.
• Keratitis: Inflammation of the cornea, which can cause pain, blurred vision, light sensitivity, and a feeling of having something in your eye. Severe or untreated keratitis can lead to vision loss.
• Blepharitis: Inflammation of the eyelids, causing redness, swelling, and crusting.
• Dry eye syndrome: Insufficient tear production, causing burning, stinging, and fluctuating vision.
• Pruritus (itching): Severe itching of the eyes and eyelids.

The Mechanism: Why Dupixent Affects the Eyes

Dupixent works by blocking IL-4 and IL-13, two key cytokines in the type 2 inflammatory pathway. This pathway is also involved in maintaining the health of the ocular surface. Researchers believe that by suppressing this pathway, Dupixent may disrupt the function of goblet cells in the conjunctiva, which are responsible for producing mucin — a critical component of the tear film that protects the eye. This disruption can lead to the inflammatory conditions listed above.

How to Document Your Symptoms

1. See an ophthalmologist: This is the most critical step. A general physician's report is not sufficient. You need a diagnosis and treatment plan from an eye specialist. Ask for a complete copy of your medical records from every visit.

2. Keep a detailed symptom journal:

• Date and time: When did the symptoms start? How long have they lasted?
• Specific symptoms: Describe the pain, redness, discharge, vision changes, etc., in as much detail as possible. Use a 1-10 scale for pain or itching.
• Photos: Take clear, well-lit photos of your eyes when they are inflamed. Date-stamp them if possible.
• Impact on daily life: Document how the symptoms have affected your ability to work, drive, read, or use screens.

3. Track all treatments and costs:

• Keep receipts for all prescription eye drops (e.g., steroid drops, cyclosporine), over-the-counter artificial tears, and other treatments.
• Keep records of all co-pays and out-of-pocket costs for ophthalmologist visits.
• Track any time missed from work due to symptoms or appointments.

4. Document communication with your prescribing doctor: Note the dates you informed your prescribing dermatologist or pulmonologist about your eye side effects and what their response was.

Legal Significance

In a potential Dupixent injury claim, this documentation is the evidence. It establishes the timeline of your injury, connects it to your Dupixent use, quantifies your medical expenses, and demonstrates the impact on your quality of life. Without this documentation, a claim is very difficult to pursue.